Biochemical Engineering
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Team

Mag. Dr. Dominik Rünzler

Rünzler_Dominik_120x90    

Institutsleiter

Studiengangsleiter Technisches Umweltmanagement und Ökotoxikologie

Stv. Studiengangsleiter Tissue Engineering and Regenerative Medicine

F&E FHplus "NewTissue" 

 

T: +43 1 333 40 77-481

E-Mail

Zur Person

Publikationen
  • Dissertation am Institut für Theoretische Chemie & Strukturbiologie der Universität Wien
  • Diplomarbeit am Institut für Organische Chemie der Universität Wien
  • Diplomstudium der Chemie/Studienzweig Biochemie an der Universität Wien

Beruflicher Werdegang

  • Seit 2007 hauptberuflich an der FH Technikum Wien
  • 2005-2007 nebenberuflicher Lektor an der FH Technikum Wien
  • 2006-2007 wissenschaftlicher Mitarbeiter am Ludwig Boltzmann Institut für Traumatologie am Lorenz Böhler Unfallkrankenhaus Wien
  • 2005-2006 Forschungsassistent an den Max F. Perutz Laboratories (Vienna Biocenter) am Institut für Biomolekulare Strukturchemie
  • 2001-2005 Forschungsassistent bei der Österreichischen Gesellschaft für Weltraummedizin am Institut für Weltraumbiophysik in Wien
  • 2000-2001 Forschungsassistent am Zentrum für NanoBiotechnologie an der Universität für Bodenkultur Wien

Tätigkeitsbereiche an der FH Technikum Wien

  • Leiter des Instituts für Biochemial Engineering
  • Aufbau des F&E Tissue Engineering Labors im Rahmen des FHplus Strukturaufbauprojekts "NewTissue“
  • Ausbau des Zellkultur- und des Umweltlabors für die Lehre im Rahmen des Gemeinde Wien Projekts "Advanced Methods für den Bio- & Umwelttechnikbereich“
  • Koordinator für die Spezialisierung "Cell & Tissue Engineering“ im Bachelor-Studiengang Biomedical Engineering sowie für das Wahlpflichtmodul „Cell & Tissue Engineering“ im Master-Studiengang Biomedical Engineering Sciences
  • Stv. Studiengangsleiter Biomedical Engineering
  • Studiengangsleiter Technisches Umweltmanagement

Schwerpunkte in der Lehre

  • Biochemie, Umweltchemie, Ökotoxikologie
  • Zellbiologie, Mikroskopie
  • Tissue Engineering

Art der Veröffentlichung

  • Artikel

    • Cieslik-Boczula, K.; Küpcü, S.; Rünzler, Dominik; Koll, A.; Köhler G.   (2009Effects of the phenolic lipid 3-pentadecylphenol on phospholipid bilayer organization  Journal of Molecular Structure / 919(1-3) / 17. Feb 2009 / S. 373-380

    • Milan-Lobo, Laura; Gsandtner, Ingrid; Gaubitzer, Erwin; Rünzler, Dominik; Buchmayer, Florian; Koehler, Gottfried; Bonci, Antonello; Freissmuth, Michael; Sitte, Harald H.  (2009Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy  MOLECULAR PHARMACOLOGY (mol pharmacol) / Dec. 2009 (76, 6): S.1196-1210

    • Milan-Lobo, L.; Gsandtner, I.; Gaubitzer, E.; Rünzler, Dominik; Buchmayer, F.; Köhler, G.; Bonci, A.; Freissmuth, M.; Sitte, HH.  (2009Subtype-specific differences in corticotropin-releasing factor receptor complexes detected by fluorescence spectroscopy  Molecular Pharmacology (mol pharmacol) Dec. 2009 (76,6) / Epub 15. Sep. 2009 / S. 1196-1210 / doi:10.1124/mol.109.059139

    • Wruss, J.; Rünzler, Dominik; Steiger, C.; Chiba, P.; Köhler, G.; Blaas, D.  (2007Attachment of VLDL receptors to an icosahedral virus along the 5-fold symmetry axis: multiple binding modes evidenced by fluorescence correlation spectroscopy  Biochemistry / 46(21) / 29. May 2007 / S. 6331-6339

    • Spurny, R.; Abdoulrahemen, K.; Janda, L.; Rünzler, Dominik; Köhler, G.; Castanon, MJ.; Wiche, G.  (2007Oxidation and nitrosylation of cysteines proximal to the intermediate filament (IF)-binding site of plectin: effects on structure and vimentin binding and involvement in IF collapse  Journal of Biological Chemistry / 282(11) / 16. March 2007 / S. 8175-8187

    • Grunt, TW.; Tomek, K.; Wagner, R.; Puckmair, K.; Kainz, B.; Rünzler, Dominik; Gaiger, A.; Zielinski, CC.; Köhler, G.  (2007Upregulation of retinoic acid receptor-beta by the epidermal growth factor-receptor inhibitor PD153035 is not mediated by blockade of ErbB pathways  Journal of Cell Physiology / 211(3) / 2007 Jun / S. 803-815

    • Maier, C.; Rünzler, Dominik; Schindelar, J.; Grabner, G.; Waldhäusl, W.; Köhler, G.; Luger, A.  (2005G-protein-coupled glucocorticoid receptors on the pituitary cell membrane  Journal of Cell Science / 118(Pt 15) / 1. Aug 2005 / S. 3353-3361

    • Huber, C.; Ilk, N.; Rünzler, Dominik; Egelseer, EM.; Weigert, S.; Sleytr, UB.; Sara, M.  (2005The three S-layer-like homology motifs of the S-layer protein SbpA of Bacillus sphaericus CCM 2177 are not sufficient for binding to the pyruvylated secondary cell wall polymer  Molecular Microbiology / 55(1) / Jan 2005 / S. 197-205

    • Huber, Carina; Illk, N.; Rünzler, Dominik; Egelseer, EM.; Weigert, S.; Sleytr, UB.; Sara, M.  (2005Thethree S-layer-like homology motifs of the S-layer protein SbpA of Bacillus sphaericus CCM 2177 are not sufficient for binding to the pyruvylated secondary cell wall polymer  Molecular Microbiology / 55(1) / Jan. 2005 / S. 197-205

    • Rünzler, Dominik; Huber, C.; Moll, D.; Köhler, G.; Sara, M.  (2004Biophysical characterization of the entire bacterial surface layer protein SbsB and its two distinct functional domains  Journal of Biological Chemistry / 279(7) / 13. Feb 2004 / S. 5207-5215

    • Rünzler, Dominik; Moll, D.; Huber, C.; Köhler, G.; Sara, M.  (2004Biophysical characterization of the entire bacterial surface layer protein SbsB and its two functional domains  Journal of Biological Chemistry / 297(7) / Feb 2004 / S. 5207-5215

    • Maier, C; Rünzler, Dominik; Wagner, L; Grabner, G; Köhler, G; Luger, A  (2002Evidence for specific glucocorticoid binding sites on the cell membrane by fluorescence correlation spectroscopy  Single Moleculus / 3(4) / 2002 / S. 211-216

  • In Buch (Kapitel/Teil einer Monographie)

    • Köhler, G.; Rünzler, Dominik; Mayer, B.; Sara, M.; Rasmussen, S.; Buravkova, L.  (2001Molecular Self-Assembly and Self-Organization in Microgravity. Applications in Biotechnology and Bioorganic Materials Sciences  10 Years Space Biomedical Research and Development in Austria / H. G. Hinghofer-Szalkay / Facultas Verlag / Vienna (Austria) / 2001 / ISBN 3-85076-572-5 / pp. 65-85

    • Gangl, S.; Stark, S.; Mayrhofer, P.; Rünzler, Dominik; Lukas, A.; Köhler, G.; Mayer, B.  (1999Molecular Organization on Giant Unilamellar Vesicles in Giant Vesicles  Perspectives in Supramolecular Chemistry / P. L. Luigi and P. Walde / J. Wiley and Sons / Vol. 6 / 1999 / ISBN 0 471 97986 / pp. 379-384

  • In Proceedings (Aufsatz / Paper einer Konferenz etc.)

    • Rünzler, Dominik; Weihs, Anna; Junger, Wolfgang G.; Sitte, Harald H.; Schaden, Wolfgang  (2012Extracorporeal shock waves - a novel method of mechanostimulation in tissue regeneration  JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

    • Frank, Martin M.; Kollmitzer, Josef; Redl, Heinz; Rünzler, Dominik  (2012Shear force stimulation of adipose-tissue derived stem cells in a novel bioreactor   JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE

    • Weihs, Anna; Knebl, Gerald; Redl, H.; Rünzler, Dominik  (2009Evaluation of cell migration methods in 3D hydrogels for tissue engineering applications  3. Forschungsforum der österreichischen Fachhochschulen / Fachhochschule Kärnten / 2009 / ISBN 978-3-853912850 / S. 490-491

    • Knebl, Gerald; Morton, T.; Redl, H.; Rünzler, Dominik  (2009Mechanical stimulation of cells in 3-dimensional fibrin constructs using a bioreactor  3. Forschungsforum der österreichischen Fachhochschulen / Fachhochschule Kärnten / 2009 / ISBN 978-3-853912850 / S. 492-493

    • Knebl, Gerhard; Weihs, Anna; Weingant, M.; Steininger, T.; Redl, T.; Rünzler, Dominik  (2008Automatisierte Datenauswertung eines Boyden-Mikro-Chemotaxis-Kammer Zell-Migrations Assays.  2. Forschungsforum der österreichischen Fachhochschulen / Dr. Johann Kastner / Verlag Shaker Verlag GmbH / 2008 / ISBN 978-3-8322-7023-0 / S. 412-417

    • Rünzler, Dominik; Knebl, Gerald; Peterbauer, A.; Wolbank, S.; Morton, T.; Redl, H.  (2008Darstellung fluoreszenzmarkierter adulter Stammzellen in drei-dimensionaler Zellkultur mittels Konfokaler Laser Scanning Mikroskopie  Erstes Forschungsforum der österreichischen Fachhochschulen / Bernhard Zimmer, Anna Koubek / Verlag Martin Meidenbauer / München / 2008 / ISBN 978-3-8997-5129-1 / S. 311-316

    • Huber, Carina; Moll, D.; Schlegel, B.; Rünzler, Dominik; Mader, C.; Sara, M.; Sleytr, UB.  (2002Recombinant S-layer-streptavidin fusion proteins: Functional protein lattices as nanoarrays for biochip development  Österr. Ges. für Hygiene, Mikrobiologie und Präventivmedizin / Proc. 28. Jahrestagung der Österr. Ges. für Hygiene, Mikrobiologie und Präventivmedizin 2002 / Meran (Südtirol)

  • Poster

    • Rünzler, Dominik  (2007Detection of Ultrafine Particles in Living Cells by using Fluorescence Correlation Spectroscopy  Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT / 2004 / Innsbruck (Austria)

    • Huber, Carina; Liu, J.; Egelseer, EM.; Rünzler, Dominik; Sara, M.; Sleytr, UB.  (2005Application Potential of Bacterial Self-Assembly Systems for Nanobiotechnology  Poster presentation at NanoBionics III-from Molecules to Applications / Book of Abstracts / Marburg (Germany) p. 77

    • Edetsberger, M.; Rünzler, Dominik; Schindelar, J.; Valic, E.; Köhler, G.  (2004Detection of Ultrafine Particles in Living Cells  8th ETH-Conference on Compustion Generated Particles / 2004 / Zürich (Schweiz)

    • Rünzler, Dominik; Maier, C.; Schindelar, J.; Grabner, G.; Köhler, G.; Luger, A.  (2004High-affinity membrane glucocorticoid binding sites on the pituitary cell line AtT-20 characterized by Fluorescence Correlation Spectroscopy  6th Annual Linz Winter Workshop: Single Molecule Techniques in Biophysics and Drug Discovery / 2004 / Linz (Austria)

    • Edetsberger, M.; Rünzler, Dominik; Schindelar, J.; Valic, E.; Köhler, G.  (2004Specific glucocorticoid binding sites on the cell membrane of AtT-20 cell line  11th Meeting of the European Neuroendocrine Association (ENEA) / 2004 / Napoli (Italy)

    • Rünzler, Dominik; Moll, D.; Huber, C.; Sleytr, UB.; Sara, M.; Köhler, G.  (2003Characterization of the Functional Domains of Bacterial Surface Layer Proteins  5th European Symposium of the Protein Society /2003 / Florence (Italy)

    • Rünzler, Dominik; Moll, D.; Huber, C.; Sleytr, UB.; Sara, M.; Köhler, G.  (2003Characterization of the Functional Domains of Bacterial Surface Layer Proteins  The 28th Lorne Conference on Protein Structure and Function / 2003 / Lorne (Australia)

    • Rünzler, Dominik; Maier, C.; Schindelar, J.; Köhler, G.; Luger, A.  (2003Fluorescence Correlation Spectroscopy (FCS): A New Tool for Studying Membrane Steroid Receptors  3rd International Meeting on Rapid Responses to Steroid Hormones / 2003 / Florence (Italy)

    • Rünzler, Dominik; Huber, C.; Sara, M.; Köhler, G.  (2003Fluorescence based Equilibrium and Kinetic Studies on Carbohydrate-Protein Binding: Interaction of Bacterial Surface Layer Proteins with their Specific Secondary Cell Wall Polymers  8th International Conference on Methods and Applications of Fluorescence Spectroscopy / 2003 / Prague (Czech Republic)

    • Maier, C.; Rünzler, Dominik; Wagner, L.; Grabner, G.; Köhler, G.; Luger, A.  (2003Further Characterization of Specific Glucocorticoid Binding on the Membrane of ACTH-Producing Pituitary Cells by Fluorescence Correlation Spectroscopy  6th European Congress of Endocrinology / 2003 / Lyon (France)

    • Maier, C.; Rünzler, Dominik; Schindelar, J.; Grabner, G.; Luger, A.  (2003High-Affinity Membrane Glucocorticoid Binding Sites on the Living Cell  3rd International Meeting on Rapid Responses to Steroid Hormones / 2003 / Florence (Italy)

    • Maier, C.; Altenberger, T.; Rünzler, Dominik; Köhler, G.; Grabner, G.; Luger, A.  (2003Investigation of putative glucocorticoid binding sites on single living cells by FCS  Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT / 2003 / Graz (Austria)

    • Maier, C.; Altenburger, T.; Rünzler, Dominik; Köhler, G.; Grabner, G.; Luger, A.  (2003Specific glucocorticoid binding sites on the cell membrane demonstrated by Fluorescence Correlation Spectroscopy  5th Annual Linz Winter Workshop: Single Molecule Techniques in Biophysics and Drug Discovery / 2002 / Linz (Austria)

    • Rünzler, Dominik; Maier, C.; Wagner, L.; Grabner, G.; Köhler, G.; Luger, A.  (2002Evidence for specific glucocorticoid binding sites on the cell membrane of a living cell by fluorescence correlation spectroscopy  Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT / 2002 / Salzburg (Austria)

    • Maier, C.; Rünzler, Dominik; Wagner, L.; Grabner, G.; Luger, A.  (2002Functional Characterization of the Putative Membrane Glucocorticoid Receptor using FCS  4th Annual Linz Winter Workshop / Single Molecule Techniques in Biophysics and Drug Discovery / 2002 / Linz (Austria)

    • Rünzler, Dominik; Sara, M.; Köhler, G.  (2001Biophysical Investigations on the S-layer Protein SbsB  Summer School: The prediction and mechanism of protein folding: from topology to intermediate states, Institut d?Etudes Scientifiques de Cargese / 2001 / Corse (France)

    • Rünzler, Dominik; Bergmann, J.; Sara, M.; Köhler, G.  (2001Protein-Ligand Interactions: Fluorescence Binding Assays performed with FCS and Fluorescence Anisotropy Measurements  FEBS Advanced Course: Microspectroscopy / Monitoring Molecular Behaviour in Living Cells / 2001 / Wageningen (Netherlands)

    • Rünzler, Dominik; Bergmann, J.; Sara, M.; Köhler, G.  (2001Protein-Ligand Interactions: Fluorescence Binding Assays performed with FCS and Fluorescence Anisotropy Measurements  FEBS Advanced Course: Microspectroscopy / Monitoring Molecular Behaviour in Living Cells / 2001 / Wageningen (Netherlands)

    • Moll, D.; Huber, Carina; Schlegel, B.; Rünzler, Dominik; Sleytr, UB.; Pum, D.; Sara, M.  (2001S-layer streptavidin fusion proteins: design of a universal template for the self-assembly of supramolecular arrays on a nanometer scale  ÖGBM, ÖGGGT, ÖGBT / Life Sciences / Joint Annual Meeting of the ÖGBM, ÖGGGT, ÖGBT / EMBnet / 2001 / Vienna (Austria)

    • Rünzler, Dominik; Sara, M.; Köhler, G.  (2000A Novel Dialysis Cell for Monitoring the Onset of Protein Nucleation using Fluorescence Spectroscopy: Experimental Setup and Investigation of Two-Dimensional Lattice Forming Surface Layer Proteins  8th International Conference on the Crystallization of Biological Macromolecules / 2000 / Florida (USA)

    • Rünzler, Dominik; Bergmann, J.; Keller, W.; Köhler, G.  (2000Protein-DNA Interactions: Comparative Study of FCS and Fluorescence Anisotropy with Conventional Gel-Retardation Assay  6th International Workshop on “Single Molecule Detection and Ultra Sensitive Analysis in Life Sciences / 2000 / Berlin (Germany)

    • Rünzler, Dominik; Sara, M.; Köhler, G.  (1999Conformational Changes of the S-layer Protein from Bacillus stearothermophilus PV72/p2 during Self-Assembly  Joint Annual Meeting of the ÖBG and ÖGGGT / 1999 / Graz (Austria)

    • Köhler, G.; Rünzler, Dominik; Mayer, B.; Sara, M.; Rasmussen, S.  (1999Effects of Gravity on Molecular Self-Assembly  NL-Gravity Symposium / 1999 / Amsterdam (The Netherlands)

    • Rünzler, Dominik; Sara, M.; Köhler, G.  (1999Equilibrium Unfolding Studies of Bacterial Surface Layer Proteins  6th International Conference on Methods and Applications of Fluorescence Spectroscopy / 1999 / Paris (France)

    • Rünzler, Dominik; Mayer, B.; Sara, M.; Köhler, G.  (1998Spectroscopic Investigations of the Disassembly-Reassembly Process of S-Layer Proteins  Joint Annual Meeting of the ÖBG and ÖGGGT / 1998 / Salzburg (Austria)

  • Vortrag

    • Rünzler, Dominik  (2008Automatisierte Datenauswertung eines Boyden-Mikro-Chemotaxis-Kammer Zell-Migrations Assays  Vortrag „2. Forschungsforum der österreichischen Fachhochschulen / 2008 / Wels (Austria)

    • Rünzler, Dominik  (2008Darstellung fluoreszenzmarkierter adulter Stammzellen in drei-dimensionaler Zellkultur mittels Konfokaler Laser Scanning Mikroskopie  Erstes Forschungsforum der österreichischen Fachhochschule / 2007 / Salzburg (Austria)

    • Rünzler, Dominik  (2003Investigation of Putative Membrane Glucocorticoid Binding Sites on Single Living Cells by FCS  Workshop on Single Molecule Detection in Living Cells / 2003 / Altleiningen (Germany)

    • Rünzler, Dominik  (1999Kristalline Zelloberflächen-Schichten-Proteine prokaryotischer Organismen (S-Schichten): Anwendungen und spektroskopische Untersuchungen  Physikalisch-chemisches Kolloquium, Institute for Physical Chemistry / 1999 / Graz (Austria)

  • Abstract

    • Milan-Lobo, L.; Rünzler, Dominik; Gaubitzer, E.; Köhler, G.; Bonci, A.; Freissmutz, M.; Sitte, HH.  (2007CRF receptors form dynamic complexes at the plasma membrane but only type 2 receptor increases lateral mobility after CRF binding  FEBS Journal / 274:210 / Jul 2007

    • Kaisler, R.; Pazmandi, C.; Ortner, A.; Haberl, I.; Köhler, G.; Rünzler, Dominik; Artl, Al.; Andreae, F.; Mosgöller, W.  (2007Vasoactive intestinal peptide conjugate internalisation as strategy for cytoplasmic drug delivery  Journal of Molecular Neuroscience / 33(3) / Sep 2007 / S. 346.

    • Huber, Carina; Moll, D.; Liu, J.; Rünzler, Dominik; Sara, M.; Sleytr, UB.  (2004Chimaeric S-Layers as Nanopatterned Biomaterials for Applications in Nanobiotechnology  Poster presentation at the 7th Annual Linz Winter Workshop / Book of Abstracts / Linz (Austria) / S. 1-10.

    • Huber, Carina; Moll, D.; Liu, J.; Rünzler, Dominik; Sara, M.; Sleytr, UB.  (2004S-Layer-Streptavidin Fusion Proteins: Novel Tools in Nanobiotechnology  Lecture at the 6th Annual Linz Winter Workshop / Book of Abstracts / Linz (Austria) S 11